TY - JOUR AU - Kazemzadeh, Farnoud AU - Kuang, Emily AU - Wong, Alexander PY - 2016/10/03 Y2 - 2024/03/28 TI - Compact, Field-Portable Lens-free Microscope using Superresolution Spatio-Spectral Light-field Fusion JF - Journal of Computational Vision and Imaging Systems JA - J. Comp. Vis. Imag. Sys. VL - 2 IS - 1 SE - Articles DO - 10.15353/vsnl.v2i1.105 UR - https://openjournals.uwaterloo.ca/index.php/vsl/article/view/105 SP - AB - <p>We present a compact, field-portable lens-free microscope based<br />on the principle of spatio-spectral light-field fusion. This is the first<br />time a device of this kind has been introduced whereby both superresolution<br />and signal-to-noise ratio are enhanced via the marriage<br />of synthetic aperture imaging and spectral light-field fusion<br />holography, culminating in a system that is self-contained and fieldportable<br />while achieving high resolution, contrast, strong signal fidelity,<br />and ultra-wide field-of-view. The active spatio-spectral illumination<br />is accomplished in the presented microscope by arranging<br />a series of pulsing LEDs emitting at different spectral wavelengths<br />in a specific spatial formation. To demonstrate the performance of<br />the presented microscope, the system was used to observe two<br />histology samples: a bovine lung, and corn stem. The imaging results<br />demonstrate the ultra-wide field-of-view advantage of the presented<br />microscope over any other system of its kind, thus enabling<br />for acquisition of the entire sample without the need for scanning,<br />while producing high-resolution, high-contrast microscopy images<br />(168 megapixels in the current system) that makes it well-suited for<br />scientific and clinical examinations.</p> ER -