Literature Review Contemporary pseudo-exfoliation glaucoma management and treatment options

Authors

  • Alexander Hynes Illinois Eye & Ear- UIC

DOI:

https://doi.org/10.15353/cjo.v86i2.5585

Keywords:

pseudoexfoliation, exfoliative glaucoma, microinvasive glaucoma surgery, ab interno trabeculectomy, cataract surgery

Abstract

Pseudoexfoliation glaucoma (PXFG) is known as the most common secondary open angle glaucoma. Accumulation of exfoliative debris in the angle and subsequent IOP elevations is thought to help make PXFG more recalcitrant to topical/medical therapy than primary open angle glaucoma. Laser therapy treatment in the form of selective laser trabeculoplasty for open angle PXFG is therefore discussed. Attention is also called however to the risk of an angle closure component in PXFG eyes and several possible mechanisms behind this. A literature-based discussion on the risks and benefits of laser peripheral iridotomy or cataract surgery to open the angle follows. Literature on the many microinvasive glaucoma surgery options (MIGS) available for PXFG is also reviewed. We provide an overview of MIGS subtypes and summarize study data on several of the better studied options for PXFG. The efficacy and risks of filtering procedures including trabeculectomy and tube shunts for PXFG is also examined.

References

Plateroti P, Plateroti AM, Abdolrahimzadeh S, Scuderi G. Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma: A Review of the Literature with Updates on Surgical Management. J Ophthalmol. 2015;2015:370371. doi:10.1155/2015/370371

Li X, He J, Sun J. LOXL1 gene polymorphisms are associated with exfoliation syndrome/exfoliation glaucoma risk: An updated meta-analysis. PLoS One. 2021;16(4):e0250772. Published 2021 Apr 28. doi:10.1371/journal.pone.0250772

Aström S, Lindén C. Incidence and prevalence of pseudoexfoliation and open-angle glaucoma in northern Sweden: I. Baseline report. Acta Ophthalmol Scand. 2007;85(8):828-831. doi:10.1111/j.1600-0420.2007.00992.x

Bedri A, Alemu B. Pseudoexfoliation syndrome in Ethiopian glaucoma patients. East Afr Med J. 1999;76(5):278-280.

Rathi S, Andrews C, Greenfield DS, Stein JD. A Comparison of Resource Use and Costs of Caring for Patients With Exfoliation Syndrome Glaucoma Versus Primary Open-Angle Glaucoma. Am J Ophthalmol. 2019;200:100-109. doi:10.1016/j.ajo.2018.12.024

Desai MA, Lee RK. The medical and surgical management of pseudoexfoliation glaucoma. Int Ophthalmol Clin. 2008;48(4):95-113. doi:10.1097/IIO.0b013e318187e902

Skaat A, Jasien JV, Ritch R. Efficacy of Topically Administered Rho-Kinase Inhibitor AR-12286 in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma. J Glaucoma. 2016;25(9):e807-e814. doi:10.1097/IJG.0000000000000508

Vesti E, Kivelä T. Exfoliation syndrome and exfoliation glaucoma. Prog Retin Eye Res. 2000;19(3):345-368. doi:10.1016/s1350-9462(99)00019-1

Tojo N, Abe S, Miyakoshi M, Hayashi A. Comparison of intraocular pressure fluctuations before and after ab interno trabeculectomy in pseudoexfoliation glaucoma patients. Clin Ophthalmol. 2017;11:1667-1675. Published 2017 Sep 14. doi:10.2147/OPTH.S143061

Konstas AG, Mantziris DA, Stewart WC. Diurnal intraocular pressure in untreated exfoliation and primary open-angle glaucoma. Arch Ophthalmol. 1997;115(2):182-185. doi:10.1001/archopht.1997.01100150184006

Koz OG, Turkcu MF, Yarangumeli A, Koz C, Kural G. Normotensive glaucoma and risk factors in normotensive eyes with pseudoexfoliation syndrome. J Glaucoma. 2009;18(9):684-688. doi:10.1097/IJG.0b013e31819c4311

Tuteja S, Zeppieri M, Chawla H. Pseudoexfoliation Syndrome and Glaucoma. [Updated 2023 May 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK574522/

Sihota R, Angmo D, Ramaswamy D, Dada T. Simplifying "target" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma. Indian J Ophthalmol. 2018;66(4):495-505. doi:10.4103/ijo.IJO_1130_17

Konstas AGP, Kozobolis VP, Katsimpris IE, et al. Efficacy and safety of latanoprost versus travoprost in exfoliative glaucoma patients. Ophthalmology 2007;114:653–657.

Konstas AG, Kozobolis VP, Katsimpris IE, et al. Efficacy and safety of latanoprost versus travoprost in exfoliative glaucoma patients. Ophthalmology. 2007;114(4):653-657. doi:10.1016/j.ophtha.2006.07.064

Konstas AG, Holló G, Irkec M, et al. Diurnal IOP control with bimatoprost versus latanoprost in exfoliative glaucoma: a crossover, observer-masked, three-centre study. Br J Ophthalmol. 2007;91(6):757-760. doi:10.1136/bjo.2006.106690

Tekeli O, Köse HC. Evaluation of the Use of Brinzolamide-Brimonidine Fixed Combination in Maximum Medical Therapy. Turk J Ophthalmol. 2022;52(4):262-269. doi:10.4274/tjo.galenos.2021.25488

Konstas AG, Maltezos A, Bufidis T, Hudgins AG, Stewart WC. Twenty-four hour control of intraocular pressure with dorzolamide and timolol maleate in exfoliation and primary open-angle glaucoma. Eye (Lond). 2000;14 ( Pt 1):73-77. doi:10.1038/eye.2000.16

Shiuey EJ, Mehran NA, Ustaoglu M, et al. The effectiveness and safety profile of netarsudil 0.02% in glaucoma treatment: real-world 6-month outcomes. Graefes Arch Clin Exp Ophthalmol 2022;260:967-74

Lo TC, Chen YY, Hung MC, Chou P. Latanoprostene Bunod 0.024% in the Treatment of Open-Angle Glaucoma and Ocular Hypertension: A Meta-Analysis. J Clin Med. 2022;11(15):4325. Published 2022 Jul 26. doi:10.3390/jcm11154325

Angelilli A, Ritch R. Directed Therapy: An Approach to the Improved Treatment of Exfoliation syndrome. Middle East Afr J Ophthalmol. 2009;16(1):35-40. doi:10.4103/0974-9233.48866

Jha B, Bhartiya S, Sharma R, Arora T, Dada T. Selective Laser Trabeculoplasty: An Overview. J Curr Glaucoma Pract. 2012;6(2):79-90. doi:10.5005/jp-journals-10008-1111

Goldenfeld M, Geyer O, Segev E, Kaplan-Messas A, Melamed S. Selective laser trabeculoplasty in uncontrolled pseudoexfoliation glaucoma. Ophthalmic Surg Lasers Imaging. 2011;42(5):390-393. doi:10.3928/15428877-20110630-01

Shazly TA, Smith J, Latina MA. Long-term safety and efficacy of selective laser trabeculoplasty as primary therapy for the treatment of pseudoexfoliation glaucoma compared with primary open-angle glaucoma. Clin Ophthalmol. 2010;5:5-10. Published 2010 Dec 16. doi:10.2147/OPTH.S15952

Wang P, Akkach S, Andrew NH, Wells AP. Selective Laser Trabeculoplasty: Outcomes of Multiple Repeat Treatments. Ophthalmol Glaucoma. 2021;4(5):482-489. doi:10.1016/j.ogla.2020.12.013

Siedlecki AR, Hicks PM, Haaland B, DeAngelis MM, Sieminski SF. Efficacy of Selective Laser Trabeculoplasty after iStent Implantation in Primary Open-Angle Glaucoma. J Pers Med. 2021;11(8):797. Published 2021 Aug 16. doi:10.3390/jpm11080797

Töteberg-Harms M, Rhee DJ. Selective laser trabeculoplasty following failed combined phacoemulsification cataract extraction and ab interno trabeculectomy. Am J Ophthalmol. 2013;156(5):936-940.e2. doi:10.1016/j.ajo.2013.05.044

Koucheki B, Hashemi H. Selective laser trabeculoplasty in the treatment of open-angle glaucoma. J Glaucoma. 2012;21:65-70. 333.

Realini T, Gazzard G, Latina M, Kass M. Low-energy Selective Laser Trabeculoplasty Repeated Annually: Rationale for the COAST Trial. J Glaucoma. 2021;30(7):545-551.

Mahdy MA. Efficacy and safety of selective laser trabeculoplasty as a primary procedure for controlling intraocular pressure in primary open angle glaucoma and ocular hypertensive patients. Sultan Qaboos Univ Med J. 2008;8(1):53-58

Bettis DI, Whitehead JJ, Farhi P, Zabriskie NA. Intraocular pressure spike and corneal decompensation following selective laser trabeculoplasty in patients with exfoliation glaucoma. J Glaucoma 2016;25:e433–7.s

Johnson PB, Katz LJ, Rhee DJ. Selective laser trabeculoplasty: predictive value of early intraocular pressure measurements for success at 3 months. Br J Ophthalmol. 2006;90(6):741-743. doi:10.1136/bjo.2005.086363

O'Brien PD, Ho SL, Fitzpatrick P, Power W. Risk factors for a postoperative intraocular pressure spike after phacoemulsification. Can J Ophthalmol. 2007;42(1):51-55.

Sarenac T, Bečić Turkanović A, Ferme P, Gračner T. A Review of Selective Laser Trabeculoplasty: "The Hype Is Real". J Clin Med. 2022;11(13):3879. Published 2022 Jul 4. doi:10.3390/jcm11133879

Chan JC, Cheung RK, Wong PW, Lai JS. Peripheral anterior synechiae after selective laser trabeculoplasty among Chinese patients. Graefes Arch Clin Exp Ophthalmol. 2022;260(11):3577-3585. doi:10.1007/s00417-022-05685-8

Kurysheva NI, Lepeshkina LV, Shatalova EO. Predictors of Outcome in Selective Laser Trabeculoplasty: A Long-term Observation Study in Primary Angle-closure Glaucoma After Laser Peripheral Iridotomy Compared With Primary Open-angle Glaucoma. J Glaucoma. 2018;27(10):880-886. doi:10.1097/IJG.0000000000001048

Kurysheva NI, Lepeshkina LV, Kapkova SG. Factors affecting the corneal endothelium after selective laser trabeculoplasty in primary open angle and angle closure glaucoma. BMJ Open Ophthalmol. 2021;6(1):e000638. Published 2021 Apr 27. doi:10.1136/bmjophth-2020-000638

Tomaszewski BT, Zalewska R, Mariak Z. Evaluation of the endothelial cell density and the central corneal thickness in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. J Ophthalmol. 2014;2014:123683. doi:10.1155/2014/123683

Örnek N, Örnek K. Corneal endothelial changes following a single session of selective laser trabeculoplasty for pseudoexfoliative glaucoma. Int Ophthalmol. 2018;38(6):2327-2333. doi:10.1007/s10792-017-0730-0

Ritch R. Exfoliation syndrome and occludable angles. Trans Am Ophthalmol Soc. 1994;92:845-944.

Gross FJ, Tingey D, Epstein DL. Increased prevalence of occludable angles and angle-closure glaucoma in patients with pseudoexfoliation. Am J Ophthalmol 1994;117:333-36. 87 80.

Al Owaifeer AM, AlObaida I, Alzuhairy S, Raheman SJ, Aljasim L, Edward DP. Frequency and risk factors of narrow angles in patients with pseudoexfoliation: a case-control study. Int Ophthalmol. 2022;42(4):1085-1091. doi:10.1007/s10792-021-02094-4.

Bartholomew RS: Pseudoexfoliation and angle-closure glaucoma. Glaucoma 1981;3:213-16.

Ritch R. Plateau Iris Is Caused by Abnormally Positioned Ciliary Processes. Journal of Glaucoma. J Glaucoma 1992;1:23-26.

Herbst RW. Angle closure glaucoma in a patient with pseudoexfoliation of the lens capsule. Ann Ophthalmol 1976;8:853-856.

Kanthan GL, Mitchell P, Burlutsky G, Rochtchina E, Wang JJ. Pseudoexfoliation syndrome and the long-term incidence of cataract and cataract surgery: the blue mountains eye study. Am J Ophthalmol. 2013;155(1):83-88.e1. doi:10.1016/j.ajo.2012.07.002

Hiller R, Sperduto RD, Krueger DE. Pseudoexfoliation, intraocular pressure, and senile lens changes in a population-based survey. Arch Ophthalmol. 1982;100(7):1080-1082. doi:10.1001/archopht.1982.01030040058007

Desai MA, Moon CS, Bretana ME, Ehlies F, Winnick M, Lee RK. Pupillary Block Glaucoma Secondary to Phacodonesis in Pseudoexfoliation. Ophthalmic Surg Lasers Imaging. Published online March 9, 2010. doi:10.3928/15428877-20100215-80

Shingleton BJ, Neo YN, Cvintal V, Shaikh AM, Liberman P, O'Donoghue MW. Outcome of phacoemulsification and intraocular lens implantion in eyes with pseudoexfoliation and weak zonules. Acta Ophthalmol. 2017;95(2):182-187. doi:10.1111/aos.13110

Qiao CY, Zhang H, Zhang Y, et al. Zhonghua Yan Ke Za Zhi. 2022;58(11):872-881. doi:10.3760/cma.j.cn112142-20211226-00608

Radhakrishnan S, Chen PP, Junk AK, Nouri-Mahdavi K, Chen TC. Laser Peripheral Iridotomy in Primary Angle Closure: A Report by the American Academy of Ophthalmology. Ophthalmology. 2018;125(7):1110-1120. doi:10.1016/j.ophtha.2018.01.015

Hu R, Wang X, Wang Y, Sun Y. Occult lens subluxation related to laser peripheral iridotomy: A case report and literature review. Medicine 2017;96:e6255.

Melamed S, Barraquer E, Epstein DL. Neodymium:YAG laser iridotomy as a possible contribution to lens dislocation. Ann Ophthalmol 1986;18:281-82.

Seong M, Kim MJ, Tchah H. Argon laser iridotomy as a possible cause of anterior dislocation of a crystalline lens. J Cataract Refract Surg 2009;35:190-92.

Zhang H, Zhang Y, Zhang S, et al. Zonulopathy Identified During Cataract Extraction in Patients With Primary Angle Closure Disease. J Glaucoma 2023;10.1097

Turaga K, Kalary J, Velamala IP. Descemet's membrane detachment after Nd:YAG laser iridotomy in a patient with pseudoexfoliation. BMJ Case Rep. 2022;15:e246071.

Liu DT, Lai JS, Lam DS. Descemet membrane detachment after sequential argon-neodymium:YAG laser peripheral iridotomy. Am J Ophthalmol. 2002;134:621-22

Ong EL, Ng J, Yong V, Yip L, Wong HT, Hee O, Thomas A, Sangtam T, Cheng J. Efficacy and safety of phacoemulsification with goniosynechialysis compared to phacoemulsification with viscosynechialysis in primary angle closure glaucoma-12 month results. Clin Exp Ophthalmol 2016;44:51

Varma D, Baylis O, Wride N, Phelan PS, Fraser SG. Viscogonioplasty: an effective procedure for lowering intraocular pressure in primary angle closure glaucoma. Eye (London, England). 2007 Apr;21(4):472-475. DOI: 10.1038/sj.eye.6702224.

Shingleton BJ, Pasternack JJ, Hung JW, O'Donoghue MW. Three and five year changes in intraocular pressures after clear corneal phacoemulsification in open angle glaucoma patients, glaucoma suspects, and normal patients. J Glaucoma 2006;15:494-498.

61 Dosso AA, Bonvin ER, Leuenberger PM. Exfoliation syndrome and phacoemulsification. J Cataract Refract Surg 1997;23:122-25.

Ramezani F, Nazarian M, Rezaei L. Intraocular pressure changes after phacoemulsification in pseudoexfoliation versus healthy eyes. BMC Ophthalmol 2021;21:198

Abdelghany AA, Sallam MA, Ellabban AA. Assessment of Ganglion Cell Complex and Peripapillary Retinal Nerve Fiber Layer Changes following Cataract Surgery in Patients with Pseudoexfoliation Glaucoma. J Ophthalmol 2019;2019:8162825. 114 357.

Damji KF, Konstas AG, Liebmann JM, et al. Intraocular pressure following phacoemulsification in patients with and without exfoliation syndrome: a 2 year prospective study. Br J Ophthalmol 2006;90:1014-18.

Masis M, Mineault PJ, Phan E, Lin SC. The role of phacoemulsification in glaucoma therapy: A systematic review and meta-analysis. Surv Ophthalmol. 2018;63(5):700-710. doi:10.1016/j.survophthal.2017.08.006

Chen PP, Lin SC, Junk AK, Radhakrishnan S, Singh K, Chen TC. The Effect of Phacoemulsification on Intraocular Pressure in Glaucoma Patients: A Report by the American Academy of Ophthalmology. Ophthalmology. 2015;122(7):1294-1307. doi:10.1016/j.ophtha.2015.03.021

Atik SS, Ugurlu S, Egrilmez ED, Ekin MA. The Effect of Uneventful Phacoemulsification on Intraocular Pressure and Anterior Segment Parameters in Pseudoexfoliation Syndrome. Beyoglu Eye J. 2020;5(3):163-168. Published 2020 Oct 28. doi:10.14744/bej.2020.08860

Holló G, Katsanos A, Konstas AG. Management of exfoliative glaucoma: challenges and solutions. Clin Ophthalmol. 2015;9:907-919. Published 2015 May 22. doi:10.2147/OPTH.S77570

Merkur A, Damji KF, Mintsioulis G, Hodge WG. Intraocular pressure decrease after phacoemulsification in patients with pseudoexfoliation syndrome. J Cataract Refract Surg. 2001;27(4):528-532. doi:10.1016/s0886-3350(00)00753-7

Rao A. Diurnal curve after phacoemulsification in patients with pseudoexfoliation syndrome and cataract. Semin Ophthalmol. 2012;27(1-2):1-5. doi:10.3109/08820538.2011.626356

Pose-Bazarra S, López-Valladares MJ, López-de-Ullibarri I, Azuara-Blanco A. Feasibility, efficacy and safety of early lens extraction in patients with pseudoexfoliation glaucoma: a feasibility and pilot study. Eye (Lond). 2023;37(9):1878-1884. doi:10.1038/s41433-022-02271-4

Vazquez-Ferreiro P, Carrera-Hueso FJ, Rodriguez LB, Diaz-Rey M, Barrios MAR, Jornet JEP. Determinants of the risk of intraoperative complications in phacoemulsification among patients with pseudoexfoliation. Saudi J Ophthalmol. 2021;35(1):5-8. Published 2021 Sep 9. doi:10.4103/1319-4534.325774

Fontana L, Coassin M, Iovieno A, Moramarco A, Cimino L. Cataract surgery in patients with pseudoex-foliation syndrome: current updates. Clin Ophthalmol. 2017;11:1377-1383. Published 2017 Jul 31. doi:10.2147/OPTH.S142870

Borkenstein AF, Borkenstein EM. Surgical experience with a redesigned, fully preloaded, hydrophobic acrylic intraocular lens in challenging cases of pseudoexfoliation syndrome, phacodonesis, and small pupils. Clin Ophthalmol 2019;13:199-06.

Ichhpujani P, Bhartiya S, Sharma A. Premium IOLs in Glaucoma. J Curr Glaucoma Pract. 2013;7(2):54-57. doi:10.5005/jp-journals-10008-1138

Arshinoff SA. Dispersive-cohesive viscoelastic soft shell technique. J Cataract Refract Surg. 1999;25(2):167-173. doi:10.1016/s0886-3350(99)80121-7

Conway RM, Schlötzer-Schrehardt U, Küchle M, Naumann GO. Pseudoexfoliation syndrome: pathological manifestations of relevance to intraocular surgery. Clin Exp Ophthalmol. 2004;32(2):199-210. doi:10.1111/j.1442-9071.2004.00806.x

Dietlein TS, Jordan J, Dinslage S, Lüke C, Krieglstein GK. Frühe postoperative Augeninnendruckspitzen nach Phakoemulsifikation bei terminalen Glaukomen [Early postoperative spikes of the intraocular pressure (IOP) following phacoemulsification in late-stage glaucoma]. Klin Monbl Augenheilkd. 2006;223(3):225-229. doi:10.1055/s-2005-858728

Jacobi PC, Dietlein TS, Krieglstein GK. Comparative study of trabecular aspiration vs trabeculectomy in glaucoma triple procedure to treat pseudoexfoliation glaucoma. Arch Ophthalmol 1999;117:1311- 18.

Georgopoulos GT, Chalkiadakis J, Livir-Rallatos G et al. Combined clear cornea phacoemulsification and trabecular aspiration in the treatment of pseudoexfoliative glaucoma associated with cataract. Graefes Arch Clin Exp Ophthalmol 2000;238:816-21.

Gedde SJ, Vinod K, Wright MM, et al. Primary Open-Angle Glaucoma Preferred Practice Pattern®. Ophthalmology. 2021;128(1):P71-P150. doi:10.1016/j.ophtha.2020.10.022

Tran VT. Washout of pseudoexfoliation material combined with cataract surgery: a new surgical approach to lower intraocular pressure in pseudoexfoliation syndrome. Int Ophthalmol. 2015;35(2):209-214. doi:10.1007/s10792-014-9934-8

Tran VT, Mansouri K, Mermoud A. Goniowash: a new surgical approach combined with cataract surgery to lower intraocular pressure in pseudoexfoliation syndrome. Int Ophthalmol. 2021;41(5):1563-1571. doi:10.1007/s10792-020-01459-5

Mathew DJ, Buys YM. Minimally Invasive Glaucoma Surgery: A Critical Appraisal of the Literature. Annu Rev Vis Sci. 2020;6:47-89. doi:10.1146/annurev-vision-121219-081737

Bloom P, Au L. "Minimally Invasive Glaucoma Surgery (MIGS) Is a Poor Substitute for Trabeculectomy"-The Great Debate. Ophthalmol Ther. 2018;7(2):203-210. doi:10.1007/s40123-018-0135-9

Hengerer FH, Auffarth GU, Riffel C, Conrad-Hengerer I. Prospective, Non-randomized, 36-Month Study of Second-Generation Trabecular Micro-Bypass Stents with Phacoemulsification in Eyes with Various Types of Glaucoma. Ophthalmol Ther. 2018;7(2):405-415. doi:10.1007/s40123-018-0152-8

Wang J, Barton K. Chapter 1- Overview of MIGS. In Sng CA, Barton K, eds. Minimally Invasive Glaucoma Surgery. Singapore: Springer; 2021:1-7.

Sarkisian SR Jr, Grover DS, Gallardo MJ, et al. Effectiveness and Safety of iStent Infinite Trabecular Micro-Bypass for Uncontrolled Glaucoma. J Glaucoma. 2023;32(1):9-18. doi:10.1097/IJG.0000000000002141

Ferguson TJ, Swan R, Ibach M, Schweitzer J, Sudhagoni R, Berdahl JP. Trabecular microbypass stent implantation with cataract extraction in pseudoexfoliation glaucoma. J Cataract Refract Surg. 2017;43(5):622-626. doi:10.1016/j.jcrs.2017.02.029

Avar M, Jordan JF, Neuburger M, et al. Long-term follow-up of intraocular pressure and pressure-lowering medication in patients after ab-interno trabeculectomy with the Trabectome. Graefes Arch Clin Exp Ophthalmol. 2019;257(5):997-1003. doi:10.1007/s00417-019-04259-5

Ting JL, Damji KF, Stiles MC; Trabectome Study Group. Ab interno trabeculectomy: outcomes in exfoliation versus primary open-angle glaucoma. J Cataract Refract Surg. 2012;38(2):315-323. doi:10.1016/j.jcrs.2011.08.043

Jordan JF, Wecker T, van Oterendorp C, et al. Trabectome surgery for primary and secondary open angle glaucomas. Graefes Arch Clin Exp Ophthalmol. 2013;251(12):2753-2760. doi:10.1007/s00417-013-2500-7

Okeke CO, Miller-Ellis E, Rojas M; Trabectome Study Group. Trabectome success factors. Medicine (Baltimore). 2017;96(24):e7061. doi:10.1097/MD.0000000000007061

Kinoshita-Nakano E, Nakanishi H, Ohashi-Ikeda H, Morooka S, Akagi T. Comparative outcomes of trabeculotomy ab externo versus trabecular ablation ab interno for open angle glaucoma. Jpn J Ophthalmol. 2018;62(2):201-208. doi:10.1007/s10384-017-0559-0

Bussel II, Kaplowitz K, Schuman JS, Loewen NA; Trabectome Study Group. Outcomes of ab interno trabeculectomy with the trabectome by degree of angle opening. Br J Ophthalmol. 2015;99(7):914-919. doi:10.1136/bjophthalmol-2014-305577

Iwasaki K, Kakimoto H, Orii Y, Arimura S, Takamura Y, Inatani M. Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma. J Clin Med. 2022;11(5):1354. Published 2022 Mar 1. doi:10.3390/jcm11051354

Barkander A, Economou MA, Jóhannesson G. Kahook Dual-Blade Goniotomy with and without Phacoemulsification in Medically Uncontrolled Glaucoma. Clin Ophthalmol. 2023;17:1385-1394. Published 2023 May 12. doi:10.2147/OPTH.S409375

Sieck EG, Epstein RS, Kennedy JB, et al. Outcomes of Kahook Dual Blade Goniotomy with and without Phacoemulsification Cataract Extraction. Ophthalmol Glaucoma. 2018;1(1):75-81. doi:10.1016/j.ogla.2018.06.006

Sharkawi E, Lindegger DJ, Artes PH, et al. Outcomes of gonioscopy-assisted transluminal trabeculotomy in pseudoexfoliative glaucoma: 24-month follow-up. Br J Ophthalmol. 2021;105(7):977-982. doi:10.1136/bjophthalmol-2020-315954

Bozkurt E, Yenihayat F, Olgun A, Yazıcı AT, Şahbaz İ. The efficacy of gonioscopy-assisted transluminal trabeculectomy combined with phacoemulsification. Int Ophthalmol. 2021;41(1):35-43. doi:10.1007/s10792-020-01550-x

Aktas Z, Ozdemir Zeydanli E, Uysal BS, Yigiter A. Outcomes of Prolene Gonioscopy Assisted Transluminal Trabeculotomy in Primary Open Angle Glaucoma and Pseudoexfoliation Glaucoma: A Comparative Study. J Glaucoma. 2022;31(9):751-756. doi:10.1097/IJG.0000000000002063

Schlenker MB, Gulamhusein H, Conrad-Hengerer I, et al. Efficacy, Safety, and Risk Factors for Failure of Standalone Ab Interno Gelatin Microstent Implantation versus Standalone Trabeculectomy [published correction appears in Ophthalmology. 2018 Mar;125(3):463]. Ophthalmology. 2017;124(11):1579-1588. doi:10.1016/j.ophtha.2017.05.004

Yang X, Zhao Y, Zhong Y, Duan X. The efficacy of XEN gel stent implantation in glaucoma: a systematic review and meta-analysis. BMC Ophthalmol. 2022;22(1):305. Published 2022 Jul 15. doi:10.1186/s12886-022-02502-y

Mansouri K, Gillmann K, Rao HL, Guidotti J, Mermoud A. Prospective Evaluation of XEN Gel Implant in Eyes With Pseudoexfoliative Glaucoma. J Glaucoma. 2018;27(10):869-873. doi:10.1097/IJG.0000000000001045

Gillmann K, Bravetti GE, Mermoud A, Rao HL, Mansouri K. XEN Gel Stent in Pseudoexfoliative Glaucoma: 2-Year Results of a Prospective Evaluation. J Glaucoma. 2019;28(8):676-684. doi:10.1097/IJG.0000000000001295

Wilkins M, Indar A, Wormald R. Intra-operative mitomycin C for glaucoma surgery. Cochrane Database Syst Rev. 2005;2005(4):CD002897. Published 2005 Oct 19. doi:10.1002/14651858.CD002897.pub2

105 Jerndal T, Kriisa V. Results of trabeculectomy for pseudo-exfoliative glaucoma. A study of 52 cases. Br J Ophthalmol. 1974;58(11):927-930. doi:10.1136/bjo.58.11.927

Popovic V, Sjöstrand J. Course of exfoliation and simplex glaucoma after primary trabeculectomy. Br J Ophthalmol. 1999;83(3):305-310. doi:10.1136/bjo.83.3.305

Gillmann K, Meduri E, Niegowski LJ, Mermoud A. Surgical Management of Pseudoexfoliative Glaucoma: A Review of Current Clinical Considerations and Surgical Outcomes. J Glaucoma. 2021;30(3):e32-e39. doi:10.1097/IJG.0000000000001724

Li F, Tang G, Zhang H, Yan X, Ma L, Geng Y. The Effects of Trabeculectomy on Pseudoexfoliation Glaucoma and Primary Open-Angle Glaucoma. J Ophthalmol. 2020;2020:1723691. Published 2020 Mar 23. doi:10.1155/2020/1723691

Rao A, Cruz RD. Cataract versus combined surgery in pseudoexfoliation glaucoma. Indian J Ophthalmol. 2023;71(3):797-802. doi:10.4103/ijo.IJO_1669_22

Gupta S, Jeria S. A Review on Glaucoma Drainage Devices and its Complications. Cureus. 2022;14(9):e29072. Published 2022 Sep 12. doi:10.7759/cureus.29072

Gedde SJ, Schiffman JC, Feuer WJ, et al. Three-year follow-up of the tube versus trabeculectomy study. Am J Ophthalmol. 2009;148(5):670-684. doi:10.1016/j.ajo.2009.06.018

Trubnik V, Zangalli C, Moster MR, et al. Evaluation of Risk Factors for Glaucoma Drainage Device-related Erosions: A Retrospective Case-Control Study. J Glaucoma. 2015;24(7):498-502. doi:10.1097/IJG.0000000000000034

Lee EK, Yun YJ, Lee JE, Yim JH, Kim CS. Changes in corneal endothelial cells after Ahmed glaucoma valve implantation: 2-year follow-up. Am J Ophthalmol. 2009;148(3):361-367. doi:10.1016/j.ajo.2009.04.016

Kim CS, Yim JH, Lee EK, Lee NH. Changes in corneal endothelial cell density and morphology after Ahmed glaucoma valve implantation during the first year of follow up. Clin Exp Ophthalmol. 2008;36(2):142-147. doi:10.1111/j.1442-9071.2008.01683.x

Palko JR, Qi O, Sheybani A. Corneal Alterations Associated with Pseudoexfoliation Syndrome and Glaucoma: A Literature Review. J Ophthalmic Vis Res. 2017;12(3):312-324. doi:10.4103/jovr.jovr_28_17

Nobl M, Freissinger S, Kassumeh S, Priglinger S, Mackert MJ. One-year outcomes of microshunt implantation in pseudoexfoliation glaucoma. PLoS One. 2021;16(8):e0256670. Published 2021 Aug 27. doi:10.1371/journal.pone.0256670

Downloads

Published

2024-07-03

How to Cite

Hynes, A. (2024). Literature Review Contemporary pseudo-exfoliation glaucoma management and treatment options . Canadian Journal of Optometry, 86(2), 7–19. https://doi.org/10.15353/cjo.v86i2.5585

Issue

Section

Original Research